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Updated April 13, 2026

How Much Do GLP-1 Medications Cost?

GLP-1 medications cost between $149/month and $1,350+/month in 2026, depending on the medication, whether you have insurance, and your chosen provider. Oral options and compounded versions have dramatically lowered the floor price this year.

Dr. Krystal A. Hughes

Medically reviewed by Dr. Krystal A. Hughes, PharmD, PhD • Last updated April 2026

Complete GLP-1 Pricing Comparison

Every GLP-1 medication currently available in the U.S., with pricing across all major pathways. Prices reflect typical monthly costs as of April 2026.

Ozempic
Injection

semaglutide

Retail

$850–$970/mo

Insurance

$25–$150/mo

Savings Card

$0–$25/mo

Compounded

N/A (diabetes only)

Telehealth

N/A

Wegovy
Injection

semaglutide

Retail

$1,349/mo

Insurance

$0–$300/mo

Savings Card

$0–$25/mo

Compounded

$297–$499/mo

Telehealth

$297–$599/mo

Wegovy Pill New
Pill

oral semaglutide

Retail

$149–$299/mo

Insurance

Pending

Savings Card

Pending

Compounded

N/A

Telehealth

$149–$299/mo

Rybelsus
Pill

semaglutide

Retail

$935/mo

Insurance

$25–$150/mo

Savings Card

$0–$10/mo

Compounded

N/A

Telehealth

N/A

Mounjaro
Injection

tirzepatide

Retail

$1,023–$1,112/mo

Insurance

$25–$150/mo

Savings Card

$0–$25/mo

Compounded

N/A (diabetes only)

Telehealth

N/A

Zepbound
Injection

tirzepatide

Retail

$1,059–$1,086/mo

Insurance

$0–$300/mo

Savings Card

$0–$25/mo

Compounded

$395–$650/mo

Telehealth

$395–$699/mo

Foundayo New
Pill

orforglipron

Retail

$149–$349/mo

Insurance

Pending

Savings Card

$25/mo

Compounded

N/A

Telehealth

Pending

Saxenda
Injection

liraglutide

Retail

$1,349/mo

Insurance

Varies

Savings Card

Limited

Compounded

N/A

Telehealth

N/A

Trulicity
Injection

dulaglutide

Retail

$994/mo

Insurance

$25–$150/mo

Savings Card

$0–$25/mo

Compounded

N/A

Telehealth

N/A

Prices are approximate and vary by pharmacy, location, and dosage. Last verified: April 13, 2026.

Cheapest GLP-1 Options in 2026

Ranked by the lowest available monthly cost, regardless of pathway.

#1
Trim Rx

Compounded semaglutide & tirzepatide

From $179/mo Start with Trim Rx →
#2
Eden Health

Compounded semaglutide (flat rate)

From $196/mo Start with Eden Health GLP-1 →
#3
Strut Health

Compounded semaglutide & tirzepatide

From $199/mo Start with Strut Health →
#4
Embody GLP-1

Injectable & oral dissolvable gum

From $199/mo Start with Embody GLP-1 →
#5
Wellorithm

Compounded semaglutide & tirzepatide

From $249/mo Start with Wellorithm GLP-1 →

How to Save on GLP-1 Medications

Concrete steps to reduce your monthly GLP-1 cost — sometimes to zero.

1. Apply for a Savings Card

Novo Nordisk and Eli Lilly both offer manufacturer savings cards that can reduce copays to $0–$25/month for commercially insured patients. Apply directly on their websites.

2. Check Your Insurance First

Call your insurer's pharmacy benefits line and ask about prior authorization requirements. Many plans now cover Wegovy and Zepbound with PA. Use our state guide to check.

3. Consider Oral GLP-1s

The Wegovy pill ($149–$299/mo) and Foundayo ($149–$349/mo) are significantly cheaper than injectable options. They're also needle-free — a win on both cost and convenience.

4. Explore Compounded Options

Compounded semaglutide ($297–$499/mo) and tirzepatide ($395–$650/mo) from telehealth providers can save 50–75% vs. retail. Compare trusted providers here.

5. Use Our Cost Calculator

Enter your medication, insurance type, and state to get a personalized cost estimate with the best available options for your situation.

Calculate Your Price →

6. Compare Before You Commit

Prices vary significantly between providers and pharmacies. Use our head-to-head comparisons and pharmacy finder to shop around.

Editor's Approved Partners

Ready to Start? Compare Our Approved Partners

After all the pricing analysis, here's where to actually go. These are the telehealth partners we have active relationships with.

Trim Rx

$199/mo

Top Pick

Patients seeking a streamlined, medically supervised GLP-1 program with transparent pricing and no insurance required

Start with Trim Rx →

Strut Health

$289/mo

Budget-conscious patients who want a low-friction onboarding with compounded semaglutide delivered quickly

Start with Strut Health →

Eden Health GLP-1

$196/mo

Patients who want integrated primary care alongside their weight management program

Start with Eden Health GLP-1 →

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Frequently Asked Questions About GLP-1 Costs

How much do GLP-1 medications cost without insurance?
Without insurance, branded GLP-1 injections cost $850–$1,350 per month at retail pharmacies. Compounded versions through telehealth providers start at $297/month for semaglutide and $395/month for tirzepatide. The new oral GLP-1 options (Wegovy pill, Foundayo) start at $149–$349/month.
What is the cheapest GLP-1 medication available in 2026?
The cheapest GLP-1 option in 2026 is the Wegovy pill (oral semaglutide) starting at $149/month through telehealth providers. Foundayo (orforglipron) is also competitively priced at $149–$349/month. For injections, compounded semaglutide starts around $297/month.
Does insurance cover GLP-1 medications?
Many insurance plans cover GLP-1 medications, especially for type 2 diabetes (Ozempic, Mounjaro). Coverage for weight loss indications (Wegovy, Zepbound) varies by plan and state. With insurance, copays typically range from $0–$300/month. Manufacturer savings cards can reduce costs to $0–$25/month for eligible patients.
Are compounded GLP-1 medications safe?
Compounded GLP-1 medications from licensed 503B pharmacies are prepared under FDA oversight and can be a safe, lower-cost alternative. However, they are not FDA-approved products themselves. Always use a reputable telehealth provider that sources from verified compounding pharmacies.
What is the difference between branded and compounded GLP-1s?
Branded GLP-1s (Ozempic, Wegovy, Zepbound) are FDA-approved manufactured products costing $850–$1,350/month retail. Compounded versions contain the same active ingredient but are mixed by compounding pharmacies at lower prices ($297–$650/month). Compounded options are available when branded versions face shortages.
Can I use a savings card for GLP-1 medications?
Yes. Novo Nordisk offers savings cards for Ozempic, Wegovy, and Rybelsus that can reduce costs to $0–$25/month for commercially insured patients. Eli Lilly offers similar programs for Mounjaro, Zepbound, and Foundayo. These cards typically cannot be used with Medicare or Medicaid.
How do oral GLP-1 pills compare in price to injections?
Oral GLP-1 options are generally cheaper than injectable versions. The Wegovy pill starts at $149–$299/month, while injectable Wegovy costs $1,349/month retail. Foundayo (orforglipron) is priced at $149–$349/month. Rybelsus, the older oral option, costs $935/month at retail.
What is the most cost-effective GLP-1 for weight loss?
For cash-pay patients, the Wegovy pill at $149–$299/month offers the best value in 2026. For those who prefer injections, compounded semaglutide at $297–$499/month is the most affordable. If you have commercial insurance with a savings card, branded options can cost as little as $0–$25/month.

All Medications

Detailed drug profiles

Compare GLP-1s

Side-by-side matchups

Cost Calculator

Personalized estimate

Provider Reviews

Telehealth ratings

All prices last verified April 13, 2026. Prices may vary by pharmacy, dosage, and location.

Affiliate Disclosure: GLP-1 Price Guide may receive a commission if you choose to utilize the services or tools linked on this page. Our research team maintains strict editorial independence to ensure objective pricing data.